Detalhe da pesquisa
1.
Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
Blood
; 141(12): 1402-1410, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375125
2.
Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.
Am J Hematol
; 99(4): 625-632, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332651
3.
Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.
N Engl J Med
; 382(26): 2524-2533, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579813
4.
Stroke Prevention with Hydroxyurea Enabled through Research and Education: A Phase 2 Primary Stroke Prevention Trial in Sub-Saharan Africa.
Acta Haematol
; 146(2): 95-105, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977532
5.
Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.
N Engl J Med
; 380(2): 121-131, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30501550
6.
Hydroxycarbamide treatment reduces transcranial Doppler velocity in the absence of transfusion support in children with sickle cell anaemia, elevated transcranial Doppler velocity, and cerebral vasculopathy: the EXTEND trial.
Br J Haematol
; 195(4): 612-620, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34291449
7.
Surveillance for sickle cell disease, United Republic of Tanzania.
Bull World Health Organ
; 98(12): 859-868, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33293746
8.
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia.
Blood
; 130(24): 2585-2593, 2017 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29051184
9.
Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.
Am J Hematol
; 93(4): 537-545, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29318647
10.
Hydroxyurea Therapy for Children With Sickle Cell Anemia in Sub-Saharan Africa: Rationale and Design of the REACH Trial.
Pediatr Blood Cancer
; 63(1): 98-104, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26275071
11.
Hydroxyurea to lower transcranial Doppler velocities and prevent primary stroke: the Uganda NOHARM sickle cell anemia cohort.
Haematologica
; 105(6): e272-e275, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31649130
12.
A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects.
Clin Pharmacokinet
; 63(3): 357-365, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401036
13.
Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.
Lancet Haematol
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38701812
14.
Sustained and Boosted Antibody Responses in Breast Milk After Maternal SARS-CoV-2 Vaccination.
Breastfeed Med
; 18(8): 612-620, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37615566
15.
Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE): an open-label, phase 2 trial.
Lancet Haematol
; 10(4): e261-e271, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870358
16.
Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease.
Trials
; 24(1): 603, 2023 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37737189
17.
Hydroxyurea Optimization through Precision Study (HOPS): study protocol for a randomized, multicenter trial in children with sickle cell anemia.
Trials
; 21(1): 983, 2020 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33246482
18.
Stroke Avoidance for Children in REpública Dominicana (SACRED): Protocol for a Prospective Study of Stroke Risk and Hydroxyurea Treatment in Sickle Cell Anemia.
JMIR Res Protoc
; 6(6): e107, 2017 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28576754
19.
Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial.
JMIR Res Protoc
; 5(2): e110, 2016 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27339303
20.
EXpanding Treatment for Existing Neurological Disease (EXTEND): An Open-Label Phase II Clinical Trial of Hydroxyurea Treatment in Sickle Cell Anemia.
JMIR Res Protoc
; 5(3): e185, 2016 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27619954